A tetrameric kinesin, Kif25, suppresses centrosome separation to establish proper spindle orientation

Microtubules tether centrosomes together during interphase (1). How this is accomplished and what benefit it provides to the cell is not known. We have identified a bipolar, minus-end directed kinesin, Kif25, that suppresses centrosome separation. Kif25 is required to prevent premature centrosome se...

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Detalles Bibliográficos
Autores principales: Decarreau, Justin, Wagenbach, Michael, Lynch, Eric, Halpern, Aaron R., Vaughan, Joshua C., Kollman, Justin, Wordeman, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376238/
https://www.ncbi.nlm.nih.gov/pubmed/28263957
http://dx.doi.org/10.1038/ncb3486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376238/
https://www.ncbi.nlm.nih.gov/pubmed/28263957
http://dx.doi.org/10.1038/ncb3486

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