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A tetrameric kinesin, Kif25, suppresses centrosome separation to establish proper spindle orientation
Microtubules tether centrosomes together during interphase (1). How this is accomplished and what benefit it provides to the cell is not known. We have identified a bipolar, minus-end directed kinesin, Kif25, that suppresses centrosome separation. Kif25 is required to prevent premature centrosome se...
Autores principales: | Decarreau, Justin, Wagenbach, Michael, Lynch, Eric, Halpern, Aaron R., Vaughan, Joshua C., Kollman, Justin, Wordeman, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376238/ https://www.ncbi.nlm.nih.gov/pubmed/28263957 http://dx.doi.org/10.1038/ncb3486 |
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