Cargando…
Effects of p53-knockout in vascular smooth muscle cells on atherosclerosis in mice
In vitro and in vivo evidence has indicated that the tumor suppressor, p53, may play a significant role in the regulation of atherosclerotic plaque formation. In vivo studies using global knockout mice models, however, have generated inconclusive results that do not address the roles of p53 in vario...
Autores principales: | Cao, Richard Yang, Eves, Robert, Jia, Lilly, Funk, Colin D., Jia, Zongchao, Mak, Alan S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376331/ https://www.ncbi.nlm.nih.gov/pubmed/28362832 http://dx.doi.org/10.1371/journal.pone.0175061 |
Ejemplares similares
-
p53 Down Regulates PDGF-Induced Formation of Circular Dorsal Ruffles in Rat Aortic Smooth Muscle Cells
por: Payne, Laura J., et al.
Publicado: (2014) -
Increased mTORC1 activity contributes to atherosclerosis in apolipoprotein E knockout mice and in vascular smooth muscle cells()
por: Ma, Kun Ling, et al.
Publicado: (2013) -
Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis
por: Ewart, Marie-Ann, et al.
Publicado: (2014) -
Senescence in Vascular Smooth Muscle Cells and Atherosclerosis
por: Zha, Yiwen, et al.
Publicado: (2022) -
Smooth muscle-specific HuR knockout induces defective autophagy and atherosclerosis
por: Liu, Shanshan, et al.
Publicado: (2021)