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Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload
Cysteine is an essential requirement in living organisms. However, due to its reactive thiol side chain, elevated levels of intracellular cysteine can be toxic and therefore need to be rapidly eliminated from the cellular milieu. In mammals and many other organisms, excess cysteine is believed to be...
Autores principales: | Deshpande, Anup Arunrao, Bhatia, Muskan, Laxman, Sunil, Bachhawat, Anand Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376351/ https://www.ncbi.nlm.nih.gov/pubmed/28435838 http://dx.doi.org/10.15698/mic2017.04.567 |
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