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Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload

Cysteine is an essential requirement in living organisms. However, due to its reactive thiol side chain, elevated levels of intracellular cysteine can be toxic and therefore need to be rapidly eliminated from the cellular milieu. In mammals and many other organisms, excess cysteine is believed to be...

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Detalles Bibliográficos
Autores principales: Deshpande, Anup Arunrao, Bhatia, Muskan, Laxman, Sunil, Bachhawat, Anand Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376351/
https://www.ncbi.nlm.nih.gov/pubmed/28435838
http://dx.doi.org/10.15698/mic2017.04.567

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