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Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study
Objectives. We conducted a one-year observational study from December 2012 to November 2013 to describe the epidemiology of bacteraemia in intensive care units (ICU) of Mohammed V Military Teaching Hospital of Rabat (Morocco). Methods. The study consisted of monitoring all blood cultures coming from...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376421/ https://www.ncbi.nlm.nih.gov/pubmed/28408938 http://dx.doi.org/10.1155/2017/4082938 |
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author | Lachhab, Zineb Frikh, Mohammed Maleb, Adil Kasouati, Jalal Doghmi, Nouafal Ben Lahlou, Yassine Belefquih, Bouchra Lemnouer, Abdelhay Elouennass, Mostafa |
author_facet | Lachhab, Zineb Frikh, Mohammed Maleb, Adil Kasouati, Jalal Doghmi, Nouafal Ben Lahlou, Yassine Belefquih, Bouchra Lemnouer, Abdelhay Elouennass, Mostafa |
author_sort | Lachhab, Zineb |
collection | PubMed |
description | Objectives. We conducted a one-year observational study from December 2012 to November 2013 to describe the epidemiology of bacteraemia in intensive care units (ICU) of Mohammed V Military Teaching Hospital of Rabat (Morocco). Methods. The study consisted of monitoring all blood cultures coming from intensive care units and studying the bacteriological profile of positive blood cultures as well as their clinical significance. Results. During this period, a total of 46 episodes of bacteraemia occurred, which corresponds to a rate of 15,4/1000 patients. The rate of nosocomial infections was 97% versus 3% for community infections. The most common source of bacteraemia was the lungs in 33%, but no source was identified in 52% of the episodes. Gram negative organisms were isolated in 83,6% of the cases with Acinetobacter baumannii being the most frequent. Antibiotic resistance was very high with 42,5% of extended-spectrum beta-lactamases (ESBLs) in Enterobacteriaceae and 100% of carbapenemase in Acinetobacter baumannii. The antibiotherapy introduced in the first 24 hours was adequate in 72% of the cases. Conclusions. Bloodstream infections in ICU occur most often in patients over 55 years, with hypertension and diabetes. The bacteria involved are mainly Gram negative bacteria multiresistant to antibiotics. Early administration of antibiotics significantly reduces patients mortality. |
format | Online Article Text |
id | pubmed-5376421 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-53764212017-04-13 Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study Lachhab, Zineb Frikh, Mohammed Maleb, Adil Kasouati, Jalal Doghmi, Nouafal Ben Lahlou, Yassine Belefquih, Bouchra Lemnouer, Abdelhay Elouennass, Mostafa Can J Infect Dis Med Microbiol Research Article Objectives. We conducted a one-year observational study from December 2012 to November 2013 to describe the epidemiology of bacteraemia in intensive care units (ICU) of Mohammed V Military Teaching Hospital of Rabat (Morocco). Methods. The study consisted of monitoring all blood cultures coming from intensive care units and studying the bacteriological profile of positive blood cultures as well as their clinical significance. Results. During this period, a total of 46 episodes of bacteraemia occurred, which corresponds to a rate of 15,4/1000 patients. The rate of nosocomial infections was 97% versus 3% for community infections. The most common source of bacteraemia was the lungs in 33%, but no source was identified in 52% of the episodes. Gram negative organisms were isolated in 83,6% of the cases with Acinetobacter baumannii being the most frequent. Antibiotic resistance was very high with 42,5% of extended-spectrum beta-lactamases (ESBLs) in Enterobacteriaceae and 100% of carbapenemase in Acinetobacter baumannii. The antibiotherapy introduced in the first 24 hours was adequate in 72% of the cases. Conclusions. Bloodstream infections in ICU occur most often in patients over 55 years, with hypertension and diabetes. The bacteria involved are mainly Gram negative bacteria multiresistant to antibiotics. Early administration of antibiotics significantly reduces patients mortality. Hindawi 2017 2017-03-19 /pmc/articles/PMC5376421/ /pubmed/28408938 http://dx.doi.org/10.1155/2017/4082938 Text en Copyright © 2017 Zineb Lachhab et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lachhab, Zineb Frikh, Mohammed Maleb, Adil Kasouati, Jalal Doghmi, Nouafal Ben Lahlou, Yassine Belefquih, Bouchra Lemnouer, Abdelhay Elouennass, Mostafa Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study |
title | Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study |
title_full | Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study |
title_fullStr | Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study |
title_full_unstemmed | Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study |
title_short | Bacteraemia in Intensive Care Unit: Clinical, Bacteriological, and Prognostic Prospective Study |
title_sort | bacteraemia in intensive care unit: clinical, bacteriological, and prognostic prospective study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376421/ https://www.ncbi.nlm.nih.gov/pubmed/28408938 http://dx.doi.org/10.1155/2017/4082938 |
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