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Engineering of Systematic Elimination of a Targeted Chromosome in Human Cells

Embryonic trisomy leads to abortion or congenital genetic disorders in humans. The most common autosomal chromosome abnormalities are trisomy of chromosomes 13, 18, and 21. Although alteration of gene dosage is thought to contribute to disorders caused by extra copies of chromosomes, genes associate...

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Detalles Bibliográficos
Autores principales:	Sato, Hiroshi, Kato, Hiroki, Yamaza, Haruyoshi, Masuda, Keiji, Nguyen, Huong Thi Nguyen, Pham, Thanh Thi Mai, Han, Xu, Hirofuji, Yuta, Nonaka, Kazuaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376435/ https://www.ncbi.nlm.nih.gov/pubmed/28401157 http://dx.doi.org/10.1155/2017/6037159

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