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Biophysical Approaches Facilitate Computational Drug Discovery for ATP-Binding Cassette Proteins

Although membrane proteins represent most therapeutically relevant drug targets, the availability of atomic resolution structures for this class of proteins has been limited. Structural characterization has been hampered by the biophysical nature of these polytopic transporters, receptors, and chann...

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Detalles Bibliográficos
Autores principales:	Molinski, Steven V., Bozóky, Zoltán, Iram, Surtaj H., Ahmadi, Saumel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376479/ https://www.ncbi.nlm.nih.gov/pubmed/28409029 http://dx.doi.org/10.1155/2017/1529402

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