Cargando…

Prospective identification of hematopoietic lineage choice by deep learning

Differentiation alters molecular properties of stem and progenitor cells, leading to changing shape and movement characteristics. We present a deep neural network that prospectively predicts lineage choice in differentiating primary hematopoietic progenitors, using image patches from brightfield mic...

Descripción completa

Detalles Bibliográficos
Autores principales: Buggenthin, Felix, Buettner, Florian, Hoppe, Philipp S, Endele, Max, Kroiss, Manuel, Strasser, Michael, Schwarzfischer, Michael, Loeffler, Dirk, Kokkaliaris, Konstantinos D, Hilsenbeck, Oliver, Schroeder, Timm, Theis, Fabian J, Marr, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376497/
https://www.ncbi.nlm.nih.gov/pubmed/28218899
http://dx.doi.org/10.1038/nmeth.4182