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Prospective identification of hematopoietic lineage choice by deep learning
Differentiation alters molecular properties of stem and progenitor cells, leading to changing shape and movement characteristics. We present a deep neural network that prospectively predicts lineage choice in differentiating primary hematopoietic progenitors, using image patches from brightfield mic...
Autores principales: | Buggenthin, Felix, Buettner, Florian, Hoppe, Philipp S, Endele, Max, Kroiss, Manuel, Strasser, Michael, Schwarzfischer, Michael, Loeffler, Dirk, Kokkaliaris, Konstantinos D, Hilsenbeck, Oliver, Schroeder, Timm, Theis, Fabian J, Marr, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376497/ https://www.ncbi.nlm.nih.gov/pubmed/28218899 http://dx.doi.org/10.1038/nmeth.4182 |
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