Cargando…
RNA-Seq Analysis of Microglia Reveals Time-Dependent Activation of Specific Genetic Programs following Spinal Cord Injury
Neurons have inherent competence to regrow following injury, although not spontaneously. Spinal cord injury (SCI) induces a pronounced neuroinflammation driven by resident microglia and infiltrating peripheral macrophages. Microglia are the first reactive glial population after SCI and participate i...
Autores principales: | Noristani, Harun N., Gerber, Yannick N., Sabourin, Jean-Charles, Le Corre, Marine, Lonjon, Nicolas, Mestre-Frances, Nadine, Hirbec, Hélène E., Perrin, Florence E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376598/ https://www.ncbi.nlm.nih.gov/pubmed/28420963 http://dx.doi.org/10.3389/fnmol.2017.00090 |
Ejemplares similares
-
Microglia Responses in Acute and Chronic Neurological Diseases: What Microglia-Specific Transcriptomic Studies Taught (and did Not Teach) Us
por: E. Hirbec, Hélène, et al.
Publicado: (2017) -
Unlike Brief Inhibition of Microglia Proliferation after Spinal Cord Injury, Long-Term Treatment Does Not Improve Motor Recovery
por: Poulen, Gaëtan, et al.
Publicado: (2021) -
Spinal cord injury induces astroglial conversion towards neuronal lineage
por: Noristani, Harun Najib, et al.
Publicado: (2016) -
Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman primates
por: Poulen, Gaëtan, et al.
Publicado: (2021) -
Correlation of in vivo and ex vivo
(1)H-MRI with histology in two severities of mouse spinal cord injury
por: Noristani, Harun N., et al.
Publicado: (2015)