Cell-free reconstitution reveals centriole cartwheel assembly mechanisms

How cellular organelles assemble is a fundamental question in biology. The centriole organelle organizes around a nine-fold symmetrical cartwheel structure typically ∼100 nm high comprising a stack of rings that each accommodates nine homodimers of SAS-6 proteins. Whether nine-fold symmetrical ring-...

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Detalles Bibliográficos
Autores principales: Guichard, P., Hamel, V., Le Guennec, M., Banterle, N., Iacovache, I., Nemčíková, V., Flückiger, I., Goldie, K. N., Stahlberg, H., Lévy, D., Zuber, B., Gönczy, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376648/
https://www.ncbi.nlm.nih.gov/pubmed/28332496
http://dx.doi.org/10.1038/ncomms14813

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