Cargando…

A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells

Individual human epidermal cells differ in their self-renewal ability. To uncover the molecular basis for this heterogeneity, we performed genome-wide pooled RNA interference screens and identified genes conferring a clonal growth advantage on normal and neoplastic (cutaneous squamous cell carcinoma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Walko, Gernot, Woodhouse, Samuel, Pisco, Angela Oliveira, Rognoni, Emanuel, Liakath-Ali, Kifayathullah, Lichtenberger, Beate M., Mishra, Ajay, Telerman, Stephanie B., Viswanathan, Priyalakshmi, Logtenberg, Meike, Renz, Lisa M., Donati, Giacomo, Quist, Sven R., Watt, Fiona M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376649/ https://www.ncbi.nlm.nih.gov/pubmed/28332498 http://dx.doi.org/10.1038/ncomms14744

Ejemplares similares

Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth
por: Telerman, Stephanie B., et al.
Publicado: (2017)

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis
por: Mishra, Ajay, et al.
Publicado: (2017)

The Roles of YAP/TAZ and the Hippo Pathway in Healthy and Diseased Skin
por: Rognoni, Emanuel, et al.
Publicado: (2019)

Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation of human epidermal cells in culture
por: Negri, Victor A., et al.
Publicado: (2019)

Micro-scaled topographies direct differentiation of human epidermal stem cells
por: Zijl, Sebastiaan, et al.
Publicado: (2019)

Biosynthesis of the Pseudomonas aeruginosa common polysaccharide antigen by D-Rhamnosyltransferases WbpX and WbpY
por: Melamed, Jacob, et al.
Publicado: (2022)

Myosin 10 is involved in murine pigmentation
por: Liakath‐Ali, Kifayathullah, et al.
Publicado: (2018)

Mutant Lef1 controls Gata6 in sebaceous gland development and cancer
por: Oulès, Bénédicte, et al.
Publicado: (2019)

The emerging roles of WBP2 oncogene in human cancers
por: Tabatabaeian, Hossein, et al.
Publicado: (2020)

Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation
por: Kaushal, Grace S, et al.
Publicado: (2015)

Reply to Chi et al.
por: Kaushal, Grace, et al.
Publicado: (2017)

Targeting the Hippo/YAP/TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
por: Howard, Alexander, et al.
Publicado: (2022)

Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing
por: Rognoni, Emanuel, et al.
Publicado: (2016)

WBP2 shares a common location in mouse spermatozoa with WBP2NL/PAWP and like its descendent is a candidate mouse oocyte-activating factor
por: Hamilton, Lauren E, et al.
Publicado: (2018)

Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
por: Rognoni, Emanuel, et al.
Publicado: (2018)

Involvement of the Wbp pathway in the biosynthesis of Porphyromonas gingivalis lipopolysaccharide with anionic polysaccharide
por: Shoji, Mikio, et al.
Publicado: (2014)

Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing
por: Buniello, Annalisa, et al.
Publicado: (2016)

Reciprocal Regulation of Hippo and WBP2 Signalling—Implications in Cancer Therapy
por: Lim, Yvonne Xinyi, et al.
Publicado: (2021)

Immunomodulatory role of Keratin 76 in oral and gastric cancer
por: Sequeira, Inês, et al.
Publicado: (2018)

WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ
por: Chan, S W, et al.
Publicado: (2011)

Elevated Expression of the Testis-specific Gene WBP2NL in Breast Cancer
por: Nourashrafeddin, Seyedmehdi, et al.
Publicado: (2015)

vhp Is a Fibrinogen-Binding Protein Related to vWbp in Staphylococcus aureus
por: Thomas, Sheila, et al.
Publicado: (2021)

WBP2 inhibits microRNA biogenesis via interaction with the microprocessor complex
por: Tabatabaeian, Hossein, et al.
Publicado: (2021)

Complete Genome Sequence of wBp, the Wolbachia Endosymbiont of Brugia pahangi FR3
por: Lebov, Jarrett F., et al.
Publicado: (2020)

WBP11 is required for splicing the TUBGCP6 pre-mRNA to promote centriole duplication
por: Park, Elizabeth M., et al.
Publicado: (2019)

Fibroblast state switching orchestrates dermal maturation and wound healing
por: Rognoni, Emanuel, et al.
Publicado: (2018)

Studies on a possible microbial aetiology for the differences in malignancy between the WBP1 sublines.
por: Williams, A. E., et al.
Publicado: (1971)

An Inhibitory Effect of Dryocrassin ABBA on Staphylococcus aureus vWbp That Protects Mice From Pneumonia
por: Li, Bangbang, et al.
Publicado: (2019)

Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis
por: Borna, Simon, et al.
Publicado: (2019)

Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair
por: Goss, Georgina, et al.
Publicado: (2021)

Loss of wbpL disrupts O‐polysaccharide synthesis and impairs virulence of plant‐associated Pseudomonas strains
por: Kutschera, Alexander, et al.
Publicado: (2019)

Galangin as a direct inhibitor of vWbp protects mice from Staphylococcus aureus‐induced pneumonia
por: Jin, Yingli, et al.
Publicado: (2021)

Characteristics of candidate genes associated with embryonic development in the cow: Evidence for a role for WBP1 in development to the blastocyst stage
por: Ortega, M. Sofia, et al.
Publicado: (2017)

Scalable topographies to support proliferation and Oct4 expression by human induced pluripotent stem cells
por: Reimer, Andreas, et al.
Publicado: (2016)

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen
por: Liakath-Ali, Kifayathullah, et al.
Publicado: (2014)

Dynamic Culture Substrates That Mimic the Topography of the Epidermal–Dermal Junction
por: Helling, Ayelen L., et al.
Publicado: (2019)

High WBP5 expression correlates with elevation of HOX genes levels and is associated with inferior survival in patients with acute myeloid leukaemia
por: Ward, C., et al.
Publicado: (2020)

WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury
por: Deng, Zebin, et al.
Publicado: (2023)

Rewiring of an Epithelial Differentiation Factor, miR-203, to Inhibit Human Squamous Cell Carcinoma Metastasis
por: Benaich, Nathan, et al.
Publicado: (2014)

Interaction of WBP2 with ERα increases doxorubicin resistance of breast cancer cells by modulating MDR1 transcription
por: Chen, Shuai, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7pb9slfb9islmpb8b26q9u8n0u