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Transfer of disrupted-in-schizophrenia 1 aggregates between neuronal-like cells occurs in tunnelling nanotubes and is promoted by dopamine

The disrupted-in-schizophrenia 1 (DISC1) gene was identified as a genetic risk factor for chronic mental illnesses (CMI) such as schizophrenia, bipolar disorder and severe recurrent depression. Insoluble aggregated DISC1 variants were found in the cingular cortex of sporadic, i.e. non-genetic, CMI p...

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Detalles Bibliográficos
Autores principales:	Zhu, Seng, Abounit, Saïda, Korth, Carsten, Zurzolo, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376705/ https://www.ncbi.nlm.nih.gov/pubmed/28275106 http://dx.doi.org/10.1098/rsob.160328

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