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Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells

Aberrant activation of telomerase occurs in 85–90% of all cancers and underpins the ability of cancer cells to bypass their proliferative limit, rendering them immortal. The activity of telomerase is tightly controlled at multiple levels, from transcriptional regulation of the telomerase components...

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Detalles Bibliográficos
Autores principales: Armstrong, Christine A., Tomita, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376709/
https://www.ncbi.nlm.nih.gov/pubmed/28330934
http://dx.doi.org/10.1098/rsob.160338

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