PPARG is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target

Angiomyolipoma (AML), the most common benign renal tumor, can result in severe morbidity from hemorrhage and renal failure. While mTORC1 activation is involved in its growth, mTORC1 inhibitors fail to eradicate AML, highlighting the need for new therapies. Moreover, the identity of the AML cell of o...

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Detalles Bibliográficos
Autores principales: Pleniceanu, Oren, Shukrun, Racheli, Omer, Dorit, Vax, Einav, Kanter, Itamar, Dziedzic, Klaudyna, Pode‐Shakked, Naomi, Mark‐Daniei, Michal, Pri‐Chen, Sara, Gnatek, Yehudit, Alfandary, Hadas, Varda‐Bloom, Nira, Bar‐Lev, Dekel D, Bollag, Naomi, Shtainfeld, Rachel, Armon, Leah, Urbach, Achia, Kalisky, Tomer, Nagler, Arnon, Harari‐Steinberg, Orit, Arbiser, Jack L, Dekel, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376758/
https://www.ncbi.nlm.nih.gov/pubmed/28275008
http://dx.doi.org/10.15252/emmm.201506111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376758/
https://www.ncbi.nlm.nih.gov/pubmed/28275008
http://dx.doi.org/10.15252/emmm.201506111

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