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Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology

Objective. Our objective was determining if abnormal Doppler evaluation had a higher prevalence of placental pathology compared to normal Doppler in suspected fetal growth restriction (FGR) of cases delivered at 37 weeks. Study Design. This retrospective cohort study of suspected FGR singletons with...

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Autores principales: Curtin, William M., Millington, Karmaine A., Ibekwe, Tochi O., Ural, Serdar H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376925/
https://www.ncbi.nlm.nih.gov/pubmed/28409154
http://dx.doi.org/10.1155/2017/3723879
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author Curtin, William M.
Millington, Karmaine A.
Ibekwe, Tochi O.
Ural, Serdar H.
author_facet Curtin, William M.
Millington, Karmaine A.
Ibekwe, Tochi O.
Ural, Serdar H.
author_sort Curtin, William M.
collection PubMed
description Objective. Our objective was determining if abnormal Doppler evaluation had a higher prevalence of placental pathology compared to normal Doppler in suspected fetal growth restriction (FGR) of cases delivered at 37 weeks. Study Design. This retrospective cohort study of suspected FGR singletons with antenatal Doppler evaluation delivered at 37 weeks had a primary outcome of the prevalence of placental pathology related to FGR. Significance was defined as p ≤ 0.05. Results. Of 100 pregnancies 46 and 54 were in the abnormal and normal Doppler cohorts, respectively. Placental pathology was more prevalent with any abnormal Doppler, 84.8% versus 55.6%, odds ratio (OR) 4.46, 95% confidence interval (CI): 1.55, 13.22, and p = 0.002. Abnormal middle cerebral artery (MCA) Doppler had a higher prevalence: 96.2% versus 54.8%, OR 20.7, 95% CI: 2.54, 447.1, and p < 0.001. Conclusion. Abnormal Doppler was associated with more placental pathology in comparison to normal Doppler in fetuses with suspected FGR. Abnormal MCA Doppler had the strongest association.
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spelling pubmed-53769252017-04-13 Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology Curtin, William M. Millington, Karmaine A. Ibekwe, Tochi O. Ural, Serdar H. Biomed Res Int Research Article Objective. Our objective was determining if abnormal Doppler evaluation had a higher prevalence of placental pathology compared to normal Doppler in suspected fetal growth restriction (FGR) of cases delivered at 37 weeks. Study Design. This retrospective cohort study of suspected FGR singletons with antenatal Doppler evaluation delivered at 37 weeks had a primary outcome of the prevalence of placental pathology related to FGR. Significance was defined as p ≤ 0.05. Results. Of 100 pregnancies 46 and 54 were in the abnormal and normal Doppler cohorts, respectively. Placental pathology was more prevalent with any abnormal Doppler, 84.8% versus 55.6%, odds ratio (OR) 4.46, 95% confidence interval (CI): 1.55, 13.22, and p = 0.002. Abnormal middle cerebral artery (MCA) Doppler had a higher prevalence: 96.2% versus 54.8%, OR 20.7, 95% CI: 2.54, 447.1, and p < 0.001. Conclusion. Abnormal Doppler was associated with more placental pathology in comparison to normal Doppler in fetuses with suspected FGR. Abnormal MCA Doppler had the strongest association. Hindawi 2017 2017-03-20 /pmc/articles/PMC5376925/ /pubmed/28409154 http://dx.doi.org/10.1155/2017/3723879 Text en Copyright © 2017 William M. Curtin et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Curtin, William M.
Millington, Karmaine A.
Ibekwe, Tochi O.
Ural, Serdar H.
Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology
title Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology
title_full Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology
title_fullStr Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology
title_full_unstemmed Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology
title_short Suspected Fetal Growth Restriction at 37 Weeks: A Comparison of Doppler and Placental Pathology
title_sort suspected fetal growth restriction at 37 weeks: a comparison of doppler and placental pathology
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376925/
https://www.ncbi.nlm.nih.gov/pubmed/28409154
http://dx.doi.org/10.1155/2017/3723879
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