Cargando…
Proteomic and functional analyses reveal pleiotropic action of the anti-tumoral compound NBDHEX in Giardia duodenalis
Giardiasis, a parasitic diarrheal disease caused by Giardia duodenalis, affects one billion people worldwide. Treatment relies only on a restricted armamentarium of drugs. The disease burden and the increase in treatment failure highlight the need for novel, safe and well characterized drug options....
Autores principales: | Camerini, Serena, Bocedi, Alessio, Cecchetti, Serena, Casella, Marialuisa, Carbo, Miriam, Morea, Veronica, Pozio, Edoardo, Ricci, Giorgio, Lalle, Marco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377010/ https://www.ncbi.nlm.nih.gov/pubmed/28366863 http://dx.doi.org/10.1016/j.ijpddr.2017.03.006 |
Ejemplares similares
-
The FAD-dependent glycerol-3-phosphate dehydrogenase of Giardia duodenalis: an unconventional enzyme that interacts with the g14-3-3 and it is a target of the antitumoral compound NBDHEX
por: Lalle, Marco, et al.
Publicado: (2015) -
Re-Discovery of Giardiavirus: Genomic and Functional Analysis of Viruses from Giardia duodenalis Isolates
por: Marucci, Gianluca, et al.
Publicado: (2021) -
The Crystal Structure of Giardia duodenalis 14-3-3 in the Apo Form: When Protein Post-Translational Modifications Make the Difference
por: Fiorillo, Annarita, et al.
Publicado: (2014) -
The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity
por: Siciliano, Giulia, et al.
Publicado: (2022) -
Severe weight loss in lambs infected with Giardia duodenalis assemblage B
por: Aloisio, Fabio, et al.
Publicado: (2006)