DNA damage-induced phosphatase Wip1 in regulation of hematopoiesis, immune system and inflammation

PP2C serine–threonine phosphatase, Wip1, is an important regulator of stress response. Wip1 controls a number of critical cellular functions: proliferation, cell cycle arrest, senescence and programmed cell death, apoptosis or autophagy. Ppm1d, the gene encoding Wip1 phosphatase, is expressed in hem...

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Detalles Bibliográficos
Autores principales: Uyanik, B, Grigorash, B B, Goloudina, A R, Demidov, O N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377063/
https://www.ncbi.nlm.nih.gov/pubmed/28417018
http://dx.doi.org/10.1038/cddiscovery.2017.18

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