Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression

Nuclear factor (NF)-κB-inducing kinase (NIK) is a serine/threonine kinase that activates NF-κB pathways, thereby regulating a wide variety of immune systems. Aberrant NIK activation causes tumor malignancy, suggesting a requirement for precise regulation of NIK activity. To explore novel interacting...

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Detalles Bibliográficos
Autores principales: Shinzawa, Miho, Konno, Hiroyasu, Qin, Junwen, Akiyama, Nobuko, Miyauchi, Maki, Ohashi, Hiroyuki, Miyamoto-Sato, Etsuko, Yanagawa, Hiroshi, Akiyama, Taishin, Inoue, Jun-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377069/
https://www.ncbi.nlm.nih.gov/pubmed/26029823
http://dx.doi.org/10.1038/srep10758

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