Cargando…
Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation
O-GlcNAcylated proteins are abundant in the brain and are associated with neuronal functions and neurodegenerative diseases. Although several studies have reported the effects of aberrant regulation of O-GlcNAcylation on brain function, the roles of O-GlcNAcylation in synaptic function remain unclea...
Autores principales: | Yang, Yong Ryoul, Song, Seungju, Hwang, Hongik, Jung, Jung Hoon, Kim, Su-Jeong, Yoon, Sora, Hur, Jin-Hoe, Park, Jae-Il, Lee, Cheol, Nam, Dougu, Seo, Young-Kyo, Kim, Joung-Hun, Rhim, Hyewhon, Suh, Pann-Ghill |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377249/ https://www.ncbi.nlm.nih.gov/pubmed/28368052 http://dx.doi.org/10.1038/srep44921 |
Ejemplares similares
-
Acutely elevated O-GlcNAcylation suppresses hippocampal activity by modulating both intrinsic and synaptic excitability factors
por: Hwang, Hongik, et al.
Publicado: (2019) -
Modulation of O-GlcNAcylation Regulates Autophagy in Cortical Astrocytes
por: Rahman, Md. Ataur, et al.
Publicado: (2019) -
O-GlcNAcylation in health and neurodegenerative diseases
por: Lee, Byeong Eun, et al.
Publicado: (2021) -
Elevated O-GlcNAcylation induces an antidepressant-like phenotype and decreased inhibitory transmission in medial prefrontal cortex
por: Cho, Yoonjeong, et al.
Publicado: (2020) -
O‐GlcNAcylation regulates lysophosphatidic acid‐induced cell migration by regulating ERM family proteins
por: Song, Minseok, et al.
Publicado: (2022)