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Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema

We studied the clinical efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema. From May 2009 to April 2013, 78 patients seeking treatment for macular edema in the First Affiliated Hospital of Nanchang University were enrolled in this study. Patients were randomly d...

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Autores principales: Shao, Yi, Yu, Yao, Li, Cheng, Pei, Chong-Gang, Tu, Ping, Han, Yun, Gao, Gui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377272/
https://www.ncbi.nlm.nih.gov/pubmed/28413496
http://dx.doi.org/10.3892/etm.2017.4145
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author Shao, Yi
Yu, Yao
Li, Cheng
Pei, Chong-Gang
Tu, Ping
Han, Yun
Gao, Gui-Ping
author_facet Shao, Yi
Yu, Yao
Li, Cheng
Pei, Chong-Gang
Tu, Ping
Han, Yun
Gao, Gui-Ping
author_sort Shao, Yi
collection PubMed
description We studied the clinical efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema. From May 2009 to April 2013, 78 patients seeking treatment for macular edema in the First Affiliated Hospital of Nanchang University were enrolled in this study. Patients were randomly divided into two groups: i) The experimental group (n=39) and the control group (n=39). Patients in the experimental group were treated with Bevacizumab (Avastin(®)) combined with argon green laser, and those in the control group were treated exclusively with argon green laser. Therapeutic effects were compared, and postoperative adverse reactions caused by both treatment methods were compared. Our results showed that, after treatment, the macular foveal thickness was reduced noticeably in both groups, while the therapeutic effect of combined treatment was more prominent. Patients in the experimental group gained the best-corrected visual acuity after one month of treatment, while patients in the control group achieved that after three months of treatment. We concluded that the use of Avastin(®) combined with argon green laser was safe and effective. Visual acuity was improved obviously with minimum adverse reactions.
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spelling pubmed-53772722017-04-15 Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema Shao, Yi Yu, Yao Li, Cheng Pei, Chong-Gang Tu, Ping Han, Yun Gao, Gui-Ping Exp Ther Med Articles We studied the clinical efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema. From May 2009 to April 2013, 78 patients seeking treatment for macular edema in the First Affiliated Hospital of Nanchang University were enrolled in this study. Patients were randomly divided into two groups: i) The experimental group (n=39) and the control group (n=39). Patients in the experimental group were treated with Bevacizumab (Avastin(®)) combined with argon green laser, and those in the control group were treated exclusively with argon green laser. Therapeutic effects were compared, and postoperative adverse reactions caused by both treatment methods were compared. Our results showed that, after treatment, the macular foveal thickness was reduced noticeably in both groups, while the therapeutic effect of combined treatment was more prominent. Patients in the experimental group gained the best-corrected visual acuity after one month of treatment, while patients in the control group achieved that after three months of treatment. We concluded that the use of Avastin(®) combined with argon green laser was safe and effective. Visual acuity was improved obviously with minimum adverse reactions. D.A. Spandidos 2017-04 2017-02-21 /pmc/articles/PMC5377272/ /pubmed/28413496 http://dx.doi.org/10.3892/etm.2017.4145 Text en Copyright: © Shao et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Shao, Yi
Yu, Yao
Li, Cheng
Pei, Chong-Gang
Tu, Ping
Han, Yun
Gao, Gui-Ping
Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema
title Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema
title_full Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema
title_fullStr Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema
title_full_unstemmed Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema
title_short Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema
title_sort clinical observation of the efficacy of bevacizumab combined with argon green laser in treating fundus macular edema
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377272/
https://www.ncbi.nlm.nih.gov/pubmed/28413496
http://dx.doi.org/10.3892/etm.2017.4145
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