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Calcitonin gene-related peptide protects type II alveolar epithelial cells from hyperoxia-induced DNA damage and cell death

Hyperoxia therapy for acute lung injury (ALI) may unexpectedly lead to reactive oxygen species (ROS) production and cause additional ALI. Calcitonin gene-related peptide (CGRP) is a 37 amino acid neuropeptide that regulates inflammasome activation. However, the role of CGRP in DNA damage during hype...

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Detalles Bibliográficos
Autores principales: Fu, Hongmin, Zhang, Tiesong, Huang, Rongwei, Yang, Zhen, Liu, Chunming, Li, Ming, Fang, Fang, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377287/
https://www.ncbi.nlm.nih.gov/pubmed/28413467
http://dx.doi.org/10.3892/etm.2017.4132