Inhibition of the TGFβ signalling pathway by cGMP and cGMP‐dependent kinase I in renal fibrosis

Agents that enhance production of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) ameliorate the progression of renal fibrosis. However, the molecular mechanism of this process is not fully understood. We hypothesize that the antifibrotic effects of cGMP and cGMP‐dependent kinase I (cGKI...

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Detalles Bibliográficos
Autores principales: Schinner, Elisabeth, Wetzl, Veronika, Schramm, Andrea, Kees, Frieder, Sandner, Peter, Stasch, Johannes‐Peter, Hofmann, Franz, Schlossmann, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377407/
https://www.ncbi.nlm.nih.gov/pubmed/28396839
http://dx.doi.org/10.1002/2211-5463.12202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377407/
https://www.ncbi.nlm.nih.gov/pubmed/28396839
http://dx.doi.org/10.1002/2211-5463.12202

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