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Activin A induces skeletal muscle catabolism via p38β mitogen‐activated protein kinase
BACKGROUND: Activation of type IIB activin receptor (ActRIIB) in skeletal muscle leads to muscle atrophy because of increased muscle protein degradation. However, the intracellular signalling mechanism that mediates ActRIIB‐activated muscle catabolism is poorly defined. METHODS: We investigated the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377410/ https://www.ncbi.nlm.nih.gov/pubmed/27897407 http://dx.doi.org/10.1002/jcsm.12145 |