Cargando…
Activin A induces skeletal muscle catabolism via p38β mitogen‐activated protein kinase
BACKGROUND: Activation of type IIB activin receptor (ActRIIB) in skeletal muscle leads to muscle atrophy because of increased muscle protein degradation. However, the intracellular signalling mechanism that mediates ActRIIB‐activated muscle catabolism is poorly defined. METHODS: We investigated the...
Autores principales: | Ding, Hui, Zhang, Guohua, Sin, Ka Wai Thomas, Liu, Zhelong, Lin, Ren‐Kuo, Li, Min, Li, Yi‐Ping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377410/ https://www.ncbi.nlm.nih.gov/pubmed/27897407 http://dx.doi.org/10.1002/jcsm.12145 |
Ejemplares similares
-
p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice
por: Liu, Zhelong, et al.
Publicado: (2018) -
p38γ Mitogen-Activated Protein Kinase Is a Key Regulator in Skeletal Muscle Metabolic Adaptation in Mice
por: Pogozelski, Andrew R., et al.
Publicado: (2009) -
p38 mitogen-activated protein kinase and mitogen-activated protein kinase-activated protein kinase 2 (MK2) signaling in atrophic and hypertrophic denervated mouse skeletal muscle
por: Evertsson, Kim, et al.
Publicado: (2014) -
Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer
por: Bauer, Jessica, et al.
Publicado: (2015) -
Weight Loss in Cancer Patients Correlates With p38β MAPK Activation in Skeletal Muscle
por: Zhang, Guohua, et al.
Publicado: (2021)