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Extracellular Vesicle-functionalized Decalcified Bone Matrix Scaffolds with Enhanced Pro-angiogenic and Pro-bone Regeneration Activities

Vascularization is crucial for bone regeneration after the transplantation of tissue-engineered bone grafts in the clinical setting. Growing evidence suggests that mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) are potently pro-angiogenic both in vitro and in vivo. In the current s...

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Detalles Bibliográficos
Autores principales: Xie, Hui, Wang, Zhenxing, Zhang, Liming, Lei, Qian, Zhao, Aiqi, Wang, Hongxiang, Li, Qiubai, Cao, Yilin, Jie Zhang, Wen, Chen, Zhichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377422/
https://www.ncbi.nlm.nih.gov/pubmed/28367979
http://dx.doi.org/10.1038/srep45622