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Cysteine persulfides and polysulfides produced by exchange reactions with H(2)S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation

Many physiological functions of hydrogen sulfide (H(2)S) have been reported in mammalian cells over the last 20 years. These physiological effects have been ascertained through in vitro treatment of cells with Na(2)S or NaHS, both of which are precursors of H(2)S. Since H(2)S exists as HS(−) in a ne...

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Detalles Bibliográficos
Autores principales: Koike, Shin, Nishimoto, Shoichi, Ogasawara, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377440/
https://www.ncbi.nlm.nih.gov/pubmed/28371750
http://dx.doi.org/10.1016/j.redox.2017.03.020