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Elevated serum 1,25(OH)(2)-vitamin D(3) level attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in kl/kl mice
Previous studies have suggested that Klotho provides reno-protection against unilateral ureteral obstruction (UUO)-induced renal tubulointerstitial fibrosis (RTF). Because the existing studies are mainly performed using heterozygous Klotho mutant (HT) mice, we focused on the effect of UUO on homozyg...
Autores principales: | Sun, Yujing, Zhou, Gengyin, Gui, Ting, Shimokado, Aiko, Nakanishi, Masako, Oikawa, Kosuke, Sato, Fuyuki, Muragaki, Yasuteru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377451/ https://www.ncbi.nlm.nih.gov/pubmed/25297969 http://dx.doi.org/10.1038/srep06563 |
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