Cargando…

TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1

Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. However, the TM4SF1-associated signaling network in metastasis remains unknown. In the present study, we found that TM4SF1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Jia-chun, Zhang, Yi, He, Si-jia, Li, Ming-ming, Cai, Xiao-lei, Wang, Hui, Xu, Lei-ming, Cao, Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377454/ https://www.ncbi.nlm.nih.gov/pubmed/28368050 http://dx.doi.org/10.1038/srep45895

Ejemplares similares

Prognostic significance of TM4SF1 and DDR1 expression in epithelial ovarian cancer
por: Huang, Zhijiong, et al.
Publicado: (2023)

TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo
por: Cao, Jia, et al.
Publicado: (2015)

TM4SF1 Promotes Proliferation, Invasion, and Metastasis in Human Liver Cancer Cells
por: Huang, Yu-Kun, et al.
Publicado: (2016)

LINC01232 exerts oncogenic activities in pancreatic adenocarcinoma via regulation of TM9SF2
por: Li, Qian, et al.
Publicado: (2019)

DDR1 promotes hepatocellular carcinoma metastasis through recruiting PSD4 to ARF6
por: Zhang, Xiaochao, et al.
Publicado: (2022)

TM4SF1 promotes esophageal squamous cell carcinoma metastasis by interacting with integrin α6
por: Hou, Sicong, et al.
Publicado: (2022)

DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis
por: Deng, Jenying, et al.
Publicado: (2021)

TM9SF4 is an F-actin disassembly factor that promotes tumor progression and metastasis
por: Meng, Zhaoyue, et al.
Publicado: (2022)

TM4SF1 is a potential target for anti-invasion and metastasis in ovarian cancer
por: Gao, Caiyun, et al.
Publicado: (2019)

Discoidin Domain Receptors, DDR1b and DDR2, Promote Tumour Growth within Collagen but DDR1b Suppresses Experimental Lung Metastasis in HT1080 Xenografts
por: Wasinski, Benjamin, et al.
Publicado: (2020)

Three Members of Transmembrane-4-Superfamily, TM4SF1, TM4SF4, and TM4SF5, as Emerging Anticancer Molecular Targets against Cancer Phenotypes and Chemoresistance
por: Rahim, Nur Syafiqah, et al.
Publicado: (2023)

TM4SF1 upregulates MYH9 to activate the NOTCH pathway to promote cancer stemness and lenvatinib resistance in HCC
por: Yang, Si-bo, et al.
Publicado: (2023)

Targeting TM4SF5 with anti-TM4SF5 monoclonal antibody suppresses the growth and motility of human pancreatic cancer cells
por: Park, Sangkyu, et al.
Publicado: (2020)

TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells
por: Kitajima, Hiroshi, et al.
Publicado: (2023)

Transmembrane-4 L-six family member-1 (TM4SF1) promotes non-small cell lung cancer proliferation, invasion and chemo-resistance through regulating the DDR1/Akt/ERK-mTOR axis
por: Ye, Lin, et al.
Publicado: (2019)

Immune‐related gene TM4SF18 could promote the metastasis of gastric cancer cells and predict the prognosis of gastric cancer patients
por: Qin, Xinyue, et al.
Publicado: (2022)

DDR1 promotes E-cadherin stability via inhibition of integrin-β1-Src activation-mediated E-cadherin endocytosis
por: Chen, Hong-Ru, et al.
Publicado: (2016)

Clinical significance of TM4SF1 as a tumor suppressor gene in gastric cancer
por: Peng, Xing‐Chun, et al.
Publicado: (2018)

DDR1 triggers epithelial cell differentiation by promoting cell adhesion through stabilization of E-cadherin
por: Yeh, Yi-Chun, et al.
Publicado: (2011)

TM4SF1 promotes the self-renewal of esophageal cancer stem-like cells and is regulated by miR-141
por: Xue, Lei, et al.
Publicado: (2016)

TM4SF18 is aberrantly expressed in pancreatic cancer and regulates cell growth
por: Singhal, Megha, et al.
Publicado: (2019)

Down-regulation of TM4SF is associated with the metastatic potential of gastric carcinoma TM4SF members in gastric carcinoma
por: Chen, Zhouxun, et al.
Publicado: (2011)

Targeting TM4SF1 exhibits therapeutic potential via inhibition of cancer stem cells
por: Chen, Guang, et al.
Publicado: (2022)

TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer
por: Tang, Qiang, et al.
Publicado: (2020)

Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling
por: Sheng, Weiwei, et al.
Publicado: (2020)

DDR1 promotes LoVo cell proliferation by regulatingenergy metabolism: Effect of DDR1 on CRC cell metabolic reprogramming
por: Xiong, Bin, et al.
Publicado: (2022)

Correction to: Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling
por: Sheng, Weiwei, et al.
Publicado: (2020)

Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome
por: Su, Hua, et al.
Publicado: (2022)

BMI1, ATM and DDR
por: Lin, Xiaozeng, et al.
Publicado: (2015)

Overexpression of DDR1 Promotes Migration, Invasion, Though EMT-Related Molecule Expression and COL4A1/DDR1/MMP-2 Signaling Axis
por: Xie, Xin, et al.
Publicado: (2020)

DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3
por: Borza, Corina M., et al.
Publicado: (2022)

Euphorbia factor L1 suppresses breast cancer liver metastasis via DDR1-mediated immune infiltration
por: Jiang, Dongjing, et al.
Publicado: (2023)

BRCA1 Reversion Mutation Confers Resistance to Olaparib and Camrelizumab in a Patient with Breast Cancer Liver Metastasis
por: Pan, Jia-Ni, et al.
Publicado: (2021)

Silencing of sinusoidal DDR1 reduces murine liver metastasis by colon carcinoma
por: Romayor, Irene, et al.
Publicado: (2020)

TWIST1 induces expression of Discoidin Domain Receptor2 (DDR2) to Promote Ovarian Cancer Metastasis
por: Grither, Whitney R., et al.
Publicado: (2018)

DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1
por: Xie, Binhui, et al.
Publicado: (2015)

Myeloid TM6SF2 Deficiency Inhibits Atherosclerosis
por: Zhu, Wenzhen, et al.
Publicado: (2022)

Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity
por: Ahn, Hye-Mi, et al.
Publicado: (2017)

N-terminus-independent activation of c-Src via binding to a tetraspan(in) TM4SF5 in hepatocellular carcinoma is abolished by the TM4SF5 C-terminal peptide application
por: Song, Haeng Eun, et al.
Publicado: (2021)

LncRNA CEBPA-DT promotes liver cancer metastasis through DDR2/β-catenin activation via interacting with hnRNPC
por: Cai, Yunshi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h10lo0a8jep4cq8kf66qo81iii