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ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice
Although high-fat diet intake is known to cause obesity and diabetes, the effect of high-fat diet itself on cognitive function remains to be clarified. We have previously shown that apoptosis signal-regulating kinase 1 (ASK1) is responsible for cognitive impairment caused by chronic cerebral hypoper...
Autores principales: | Toyama, Kensuke, Koibuchi, Nobutaka, Hasegawa, Yu, Uekawa, Ken, Yasuda, Osamu, Sueta, Daisuke, Nakagawa, Takashi, Ma, Mingjie, Kusaka, Hiroaki, Lin, Bowen, Ogawa, Hisao, Ichijo, Hidenori, Kim-Mitsuyama, Shokei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377457/ https://www.ncbi.nlm.nih.gov/pubmed/26044555 http://dx.doi.org/10.1038/srep10844 |
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