Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway

miR-3127-5p is a primate-specific miRNA which is down-regulated in recurrent NSCLC tissue vs. matched primary tumor tissue (N = 15) and in tumor tissue vs. normal lung tissue (N = 177). Reduced miR-3127-5p expression is associated with a higher Ki-67 proliferation index and unfavorable prognosis in...

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Detalles Bibliográficos
Autores principales: Sun, Yifeng, Chen, Chang, Zhang, Peng, Xie, Huikang, Hou, Likun, Hui, Zheng, Xu, Yongjie, Du, Qiaoling, Zhou, Xiao, Su, Bo, Gao, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377463/
https://www.ncbi.nlm.nih.gov/pubmed/25284075
http://dx.doi.org/10.1038/srep06527

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