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Oral intake of curcumin markedly activated CYP 3A4: in vivo and ex-vivo studies

Curcumin, a specific secondary metabolite of Curcuma species, has potentials for a variety of beneficial health effects. It is nowadays used as a dietary supplement. Everolimus (EVL) is an immunosuppressant indicated for allograft rejection and cancer therapy, but with narrow therapeutic window. EVL...

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Detalles Bibliográficos
Autores principales:	Hsieh, Yow-Wen, Huang, Ching-Ya, Yang, Shih-Ying, Peng, Yu-Hsuan, Yu, Chung-Ping, Chao, Pei-Dawn Lee, Hou, Yu-Chi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377466/ https://www.ncbi.nlm.nih.gov/pubmed/25300360 http://dx.doi.org/10.1038/srep06587

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