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Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death

Glycolytic glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional protein that also mediates cell death under oxidative stress. We reported previously that the active-site cysteine (Cys-152) of GAPDH plays an essential role in oxidative stress-induced aggregation of GAPDH associated w...

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Detalles Bibliográficos
Autores principales:	Nakajima, Hidemitsu, Itakura, Masanori, Kubo, Takeya, Kaneshige, Akihiro, Harada, Naoki, Izawa, Takeshi, Azuma, Yasu-Taka, Kuwamura, Mitsuru, Yamaji, Ryouichi, Takeuchi, Tadayoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377786/ https://www.ncbi.nlm.nih.gov/pubmed/28167533 http://dx.doi.org/10.1074/jbc.M116.759084

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