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The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency
OBJECTIVE: to compare the clinical and cost-effectiveness of a Community In-reach Rehabilitation and Care Transition (CIRACT) service with the traditional hospital-based rehabilitation (THB-Rehab) service. DESIGN: pragmatic randomised controlled trial with an integral health economic study. SETTINGS...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377906/ https://www.ncbi.nlm.nih.gov/pubmed/28180236 http://dx.doi.org/10.1093/ageing/afw149 |
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author | Sahota, Opinder Pulikottil-Jacob, Ruth Marshall, Fiona Montgomery, Alan Tan, Wei Sach, Tracey Logan, Pip Kendrick, Denise Watson, Alison Walker, Maria Waring, Justin |
author_facet | Sahota, Opinder Pulikottil-Jacob, Ruth Marshall, Fiona Montgomery, Alan Tan, Wei Sach, Tracey Logan, Pip Kendrick, Denise Watson, Alison Walker, Maria Waring, Justin |
author_sort | Sahota, Opinder |
collection | PubMed |
description | OBJECTIVE: to compare the clinical and cost-effectiveness of a Community In-reach Rehabilitation and Care Transition (CIRACT) service with the traditional hospital-based rehabilitation (THB-Rehab) service. DESIGN: pragmatic randomised controlled trial with an integral health economic study. SETTINGS: large UK teaching hospital, with community follow-up. SUBJECTS: frail older people aged 70 years and older admitted to hospital as an acute medical emergency. MEASUREMENTS: Primary outcome: hospital length of stay; secondary outcomes: readmission, day 91-super spell bed days, functional ability, co-morbidity and health-related quality of life; cost-effectiveness analysis. RESULTS: a total of 250 participants were randomised. There was no significant difference in length of stay between the CIRACT and THB-Rehab service (median 8 versus 9 days; geometric mean 7.8 versus 8.7 days, mean ratio 0.90, 95% confidence interval (CI) 0.74–1.10). Of the participants who were discharged from hospital, 17% and 13% were readmitted within 28 days from the CIRACT and THB-Rehab services, respectively (risk difference 3.8%, 95% CI −5.8% to 13.4%). There were no other significant differences in any of the other secondary outcomes between the two groups. The mean costs (including NHS and personal social service) of the CIRACT and THB-Rehab service were £3,744 and £3,603, respectively (mean cost difference £144; 95% CI −1,645 to 1,934). CONCLUSION: the CIRACT service does not reduce major hospital length of stay nor reduce short-term readmission rates, compared to the standard THB-Rehab service; however, a modest (<2.3 days) effect cannot be excluded. Further studies are necessary powered with larger sample sizes and cluster randomisation. TRIAL REGISTRATION: ISRCTN 94393315, 25th April 2013 |
format | Online Article Text |
id | pubmed-5377906 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-53779062017-04-10 The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency Sahota, Opinder Pulikottil-Jacob, Ruth Marshall, Fiona Montgomery, Alan Tan, Wei Sach, Tracey Logan, Pip Kendrick, Denise Watson, Alison Walker, Maria Waring, Justin Age Ageing Research Paper OBJECTIVE: to compare the clinical and cost-effectiveness of a Community In-reach Rehabilitation and Care Transition (CIRACT) service with the traditional hospital-based rehabilitation (THB-Rehab) service. DESIGN: pragmatic randomised controlled trial with an integral health economic study. SETTINGS: large UK teaching hospital, with community follow-up. SUBJECTS: frail older people aged 70 years and older admitted to hospital as an acute medical emergency. MEASUREMENTS: Primary outcome: hospital length of stay; secondary outcomes: readmission, day 91-super spell bed days, functional ability, co-morbidity and health-related quality of life; cost-effectiveness analysis. RESULTS: a total of 250 participants were randomised. There was no significant difference in length of stay between the CIRACT and THB-Rehab service (median 8 versus 9 days; geometric mean 7.8 versus 8.7 days, mean ratio 0.90, 95% confidence interval (CI) 0.74–1.10). Of the participants who were discharged from hospital, 17% and 13% were readmitted within 28 days from the CIRACT and THB-Rehab services, respectively (risk difference 3.8%, 95% CI −5.8% to 13.4%). There were no other significant differences in any of the other secondary outcomes between the two groups. The mean costs (including NHS and personal social service) of the CIRACT and THB-Rehab service were £3,744 and £3,603, respectively (mean cost difference £144; 95% CI −1,645 to 1,934). CONCLUSION: the CIRACT service does not reduce major hospital length of stay nor reduce short-term readmission rates, compared to the standard THB-Rehab service; however, a modest (<2.3 days) effect cannot be excluded. Further studies are necessary powered with larger sample sizes and cluster randomisation. TRIAL REGISTRATION: ISRCTN 94393315, 25th April 2013 Oxford University Press 2017-01 2016-10-06 /pmc/articles/PMC5377906/ /pubmed/28180236 http://dx.doi.org/10.1093/ageing/afw149 Text en © The Author 2016. Published by Oxford University Press on behalf of the British Geriatrics Society. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Research Paper Sahota, Opinder Pulikottil-Jacob, Ruth Marshall, Fiona Montgomery, Alan Tan, Wei Sach, Tracey Logan, Pip Kendrick, Denise Watson, Alison Walker, Maria Waring, Justin The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency |
title | The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency |
title_full | The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency |
title_fullStr | The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency |
title_full_unstemmed | The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency |
title_short | The Community In-reach Rehabilitation and Care Transition (CIRACT) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency |
title_sort | community in-reach rehabilitation and care transition (ciract) clinical and cost-effectiveness randomisation controlled trial in older people admitted to hospital as an acute medical emergency |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377906/ https://www.ncbi.nlm.nih.gov/pubmed/28180236 http://dx.doi.org/10.1093/ageing/afw149 |
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