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Broad-Based CD4(+) T Cell Responses to Influenza A Virus in a Healthy Individual Who Lacks Typical Immunodominance Hierarchy
Influenza A virus (IAV) infection is a significant cause of morbidity and mortality worldwide. CD4(+) T cell responses have been shown to be important for influenza protection in mouse models and in human volunteers. IAV antigen-specific CD4(+) T cell responses were found to focus on matrix 1 (M1) a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377932/ https://www.ncbi.nlm.nih.gov/pubmed/28421076 http://dx.doi.org/10.3389/fimmu.2017.00375 |