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Tenofovir Inhibits Wound Healing of Epithelial Cells and Fibroblasts from the Upper and Lower Human Female Reproductive Tract

Disruption of the epithelium in the female reproductive tract (FRT) is hypothesized to increase HIV infection risk by interfering with barrier protection and facilitating HIV-target cell recruitment. Here we determined whether Tenofovir (TFV), used vaginally in HIV prevention trials, and Tenofovir a...

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Detalles Bibliográficos
Autores principales: Rodriguez-Garcia, Marta, Patel, Mickey V., Shen, Zheng, Bodwell, Jack, Rossoll, Richard M., Wira, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377941/
https://www.ncbi.nlm.nih.gov/pubmed/28368028
http://dx.doi.org/10.1038/srep45725