Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation

Patterns of gene expression in tumors can arise as a consequence of or result in genomic instability, characterized by the accumulation of somatic copy number alterations (SCNAs) and point mutations (PMs). Expression signatures have been widely used as markers for genomic instability, and both SCNAs...

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Detalles Bibliográficos
Autores principales: Buccitelli, Christopher, Salgueiro, Lorena, Rowald, Konstantina, Sotillo, Rocio, Mardin, Balca R., Korbel, Jan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378169/
https://www.ncbi.nlm.nih.gov/pubmed/28320919
http://dx.doi.org/10.1101/gr.212225.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378169/
https://www.ncbi.nlm.nih.gov/pubmed/28320919
http://dx.doi.org/10.1101/gr.212225.116

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