Cargando…
Network-based proteomic approaches reveal the neurodegenerative, neuroprotective and pain-related mechanisms involved after retrograde axonal damage
Neurodegenerative processes are preceded by neuronal dysfunction and synaptic disconnection. Disconnection between spinal motoneuron (MN) soma and synaptic target leads either to a retrograde degenerative process or to a regenerative reaction, depending injury proximity among other factors. Distingu...
Autores principales: | Casas, Caty, Isus, Laura, Herrando-Grabulosa, Mireia, Mancuso, Francesco M., Borrás, Eva, Sabidó, Eduardo, Forés, Joaquim, Aloy, Patrick |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378195/ https://www.ncbi.nlm.nih.gov/pubmed/25784190 http://dx.doi.org/10.1038/srep09185 |
Ejemplares similares
-
ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons
por: Leiva-Rodríguez, Tatiana, et al.
Publicado: (2018) -
Novel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked Systems
por: Herrando-Grabulosa, Mireia, et al.
Publicado: (2016) -
Neuroprotective Drug for Nerve Trauma Revealed Using Artificial Intelligence
por: Romeo-Guitart, David, et al.
Publicado: (2018) -
GRP78 Overexpression Triggers PINK1-IP(3)R-Mediated Neuroprotective Mitophagy
por: Leiva-Rodríguez, Tatiana, et al.
Publicado: (2021) -
Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosis
por: Casas, Caty, et al.
Publicado: (2013)