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Degree of methylation burden is determined by the exposure period to carcinogenic factors
Aberrant DNA methylation accumulated in normal tissues, namely methylation burden, is associated with risk of carcinogenesis. The levels of methylation burden are known to be influenced by multiple factors, such as genetic factors and strengths of carcinogenic factors. However, the impact of the deg...
Autores principales: | Takeshima, Hideyuki, Niwa, Tohru, Toyoda, Takeshi, Wakabayashi, Mika, Yamashita, Satoshi, Ushijima, Toshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378290/ https://www.ncbi.nlm.nih.gov/pubmed/27992956 http://dx.doi.org/10.1111/cas.13136 |
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