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Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014

Tumours of the Central Nervous System (CNS) are an important cause of mortality from cancer. Epidemiological data on neoplams affecting the CNS are scarce in Brazil, especially in the Amazon region. The study aims at describing the histopathological profile of CNS tumours cases at a high-complexity...

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Detalles Bibliográficos
Autores principales: Werneck de Carvalho, Luis Eduardo, Sarraf, Jonathan Souza, Semblano, Aluízio Augusto Pereira, Moreira, Matheus Acácio, de Lemos, Manuela Nascimento, de Mello, Vanessa Jóia, Hamoy, Moisés, Nazareth Junior, Mario Hermes, Paschoal Junior, Fernando Mendes, Adami, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378382/
https://www.ncbi.nlm.nih.gov/pubmed/28369089
http://dx.doi.org/10.1371/journal.pone.0174439
Descripción
Sumario:Tumours of the Central Nervous System (CNS) are an important cause of mortality from cancer. Epidemiological data on neoplams affecting the CNS are scarce in Brazil, especially in the Amazon region. The study aims at describing the histopathological profile of CNS tumours cases at a high-complexity referral cancer center. This study has described a 17-year-series profile of CNS tumours, registered at a high-complexity referral cancer center in Pará state, from January 1997 until July 2014 in the Brazilian Amazon Region. Data was gathered from histopathology reports kept in the hospital’s cancer registry and 949 cases of CNS tumours were analyzed. The most common histopathology were neuroepithelial tumours (approx. 40%) and meningioma was the most frequent especific tumor histologic subtype (22.2%). Neuroepithelial tumours were more frequent in patients with ages ranging from less than a year to 19 years, whereas metastatic tumours were prevalent in patients over 40 years of age. It was not found temporal trends during the studied period. The knowledge of these tumours profile is valuable for the understanding of cancer epidemiology in the region, since its prevalence is currently underreported and more awareness on the disease is needed.