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Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014
Tumours of the Central Nervous System (CNS) are an important cause of mortality from cancer. Epidemiological data on neoplams affecting the CNS are scarce in Brazil, especially in the Amazon region. The study aims at describing the histopathological profile of CNS tumours cases at a high-complexity...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378382/ https://www.ncbi.nlm.nih.gov/pubmed/28369089 http://dx.doi.org/10.1371/journal.pone.0174439 |
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author | Werneck de Carvalho, Luis Eduardo Sarraf, Jonathan Souza Semblano, Aluízio Augusto Pereira Moreira, Matheus Acácio de Lemos, Manuela Nascimento de Mello, Vanessa Jóia Hamoy, Moisés Nazareth Junior, Mario Hermes Paschoal Junior, Fernando Mendes Adami, Fernando |
author_facet | Werneck de Carvalho, Luis Eduardo Sarraf, Jonathan Souza Semblano, Aluízio Augusto Pereira Moreira, Matheus Acácio de Lemos, Manuela Nascimento de Mello, Vanessa Jóia Hamoy, Moisés Nazareth Junior, Mario Hermes Paschoal Junior, Fernando Mendes Adami, Fernando |
author_sort | Werneck de Carvalho, Luis Eduardo |
collection | PubMed |
description | Tumours of the Central Nervous System (CNS) are an important cause of mortality from cancer. Epidemiological data on neoplams affecting the CNS are scarce in Brazil, especially in the Amazon region. The study aims at describing the histopathological profile of CNS tumours cases at a high-complexity referral cancer center. This study has described a 17-year-series profile of CNS tumours, registered at a high-complexity referral cancer center in Pará state, from January 1997 until July 2014 in the Brazilian Amazon Region. Data was gathered from histopathology reports kept in the hospital’s cancer registry and 949 cases of CNS tumours were analyzed. The most common histopathology were neuroepithelial tumours (approx. 40%) and meningioma was the most frequent especific tumor histologic subtype (22.2%). Neuroepithelial tumours were more frequent in patients with ages ranging from less than a year to 19 years, whereas metastatic tumours were prevalent in patients over 40 years of age. It was not found temporal trends during the studied period. The knowledge of these tumours profile is valuable for the understanding of cancer epidemiology in the region, since its prevalence is currently underreported and more awareness on the disease is needed. |
format | Online Article Text |
id | pubmed-5378382 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-53783822017-04-07 Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014 Werneck de Carvalho, Luis Eduardo Sarraf, Jonathan Souza Semblano, Aluízio Augusto Pereira Moreira, Matheus Acácio de Lemos, Manuela Nascimento de Mello, Vanessa Jóia Hamoy, Moisés Nazareth Junior, Mario Hermes Paschoal Junior, Fernando Mendes Adami, Fernando PLoS One Research Article Tumours of the Central Nervous System (CNS) are an important cause of mortality from cancer. Epidemiological data on neoplams affecting the CNS are scarce in Brazil, especially in the Amazon region. The study aims at describing the histopathological profile of CNS tumours cases at a high-complexity referral cancer center. This study has described a 17-year-series profile of CNS tumours, registered at a high-complexity referral cancer center in Pará state, from January 1997 until July 2014 in the Brazilian Amazon Region. Data was gathered from histopathology reports kept in the hospital’s cancer registry and 949 cases of CNS tumours were analyzed. The most common histopathology were neuroepithelial tumours (approx. 40%) and meningioma was the most frequent especific tumor histologic subtype (22.2%). Neuroepithelial tumours were more frequent in patients with ages ranging from less than a year to 19 years, whereas metastatic tumours were prevalent in patients over 40 years of age. It was not found temporal trends during the studied period. The knowledge of these tumours profile is valuable for the understanding of cancer epidemiology in the region, since its prevalence is currently underreported and more awareness on the disease is needed. Public Library of Science 2017-04-03 /pmc/articles/PMC5378382/ /pubmed/28369089 http://dx.doi.org/10.1371/journal.pone.0174439 Text en © 2017 Werneck de Carvalho et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Werneck de Carvalho, Luis Eduardo Sarraf, Jonathan Souza Semblano, Aluízio Augusto Pereira Moreira, Matheus Acácio de Lemos, Manuela Nascimento de Mello, Vanessa Jóia Hamoy, Moisés Nazareth Junior, Mario Hermes Paschoal Junior, Fernando Mendes Adami, Fernando Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014 |
title | Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014 |
title_full | Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014 |
title_fullStr | Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014 |
title_full_unstemmed | Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014 |
title_short | Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014 |
title_sort | central nervous system tumours profile at a referral center in the brazilian amazon region, 1997–2014 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378382/ https://www.ncbi.nlm.nih.gov/pubmed/28369089 http://dx.doi.org/10.1371/journal.pone.0174439 |
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