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p53 pathway determines the cellular response to alcohol-induced DNA damage in MCF-7 breast cancer cells

Alcohol consumption is associated with increased breast cancer risk; however, the underlying mechanisms that contribute to mammary tumor initiation and progression are unclear. Alcohol is known to induce oxidative stress and DNA damage; likewise, p53 is a critical modulator of the DNA repair pathway...

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Detalles Bibliográficos
Autores principales:	Zhao, Ming, Howard, Erin W., Guo, Zhiying, Parris, Amanda B., Yang, Xiaohe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378409/ https://www.ncbi.nlm.nih.gov/pubmed/28369097 http://dx.doi.org/10.1371/journal.pone.0175121

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