Cargando…

Decitabine reverses TGF-β1-induced epithelial–mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis

OBJECTIVE: Epithelial–mesenchymal transition (EMT) is a crucial driver of tumor progression. Tumor growth factor-beta 1 (TGF-β1) is an important factor in EMT induction in tumorigenesis. The targeting of EMT may, therefore, represent a promising approach in anticancer treatment. METHODS: In this stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Nan, Liu, Yanyang, Wang, Yuyi, Zhao, Maoyuan, Tu, Li, Luo, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378468/ https://www.ncbi.nlm.nih.gov/pubmed/28405157 http://dx.doi.org/10.2147/DDDT.S129305

Ejemplares similares

Decitabine reverses TGF-β1-induced epithelial–mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis [Corrigendum]
Publicado: (2017)

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
por: Gregory, Philip A., et al.
Publicado: (2011)

miR-200c Prevents TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis in Mesothelial Cells by Targeting ZEB2 and Notch1
por: Chu, Jessica Y.S., et al.
Publicado: (2019)

miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1
por: Gao, Hai-Xiang, et al.
Publicado: (2016)

miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma
por: GUO, FEI, et al.
Publicado: (2014)

Reversal of transforming growth factor-β induced epithelial-to-mesenchymal transition and the ZEB proteins
por: Das, Shreyasi, et al.
Publicado: (2012)

ZEB1/miR-200c/AGR2: A New Regulatory Loop Modulating the Epithelial-Mesenchymal Transition in Lung Adenocarcinomas
por: Sommerova, Lucia, et al.
Publicado: (2020)

LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process
por: Sun, Zhenqiang, et al.
Publicado: (2021)

TMPRSS2/ERG Promotes Epithelial to Mesenchymal Transition through the ZEB1/ZEB2 Axis in a Prostate Cancer Model
por: Leshem, Orit, et al.
Publicado: (2011)

circ-ZEB1 regulates epithelial-mesenchymal transition and chemotherapy resistance of colorectal cancer through acting on miR-200c-5p
por: Chen, Hongyu, et al.
Publicado: (2022)

Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway
por: Das, Shreyas, et al.
Publicado: (2009)

Long non-coding RNA linc00645 promotes TGF-β-induced epithelial–mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma
por: Li, Chenlong, et al.
Publicado: (2019)

miR-200b inhibits TGF-β1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells
por: Chen, Y, et al.
Publicado: (2013)

TBX1 targets the miR-200–ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties
por: Funato, Noriko, et al.
Publicado: (2022)

The VIM-AS1/miR-655/ZEB1 axis modulates bladder cancer cell metastasis by regulating epithelial–mesenchymal transition
por: Xiong, Yaoyao, et al.
Publicado: (2021)

Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1
por: Carriere, Patrick P., et al.
Publicado: (2015)

Mutant p53 gain-of-function induces epithelial–mesenchymal transition through modulation of the miR-130b–ZEB1 axis
por: Dong, P, et al.
Publicado: (2013)

Tumor‐suppressive roles of ΔNp63β‐miR‐205 axis in epithelial–mesenchymal transition of oral squamous cell carcinoma via targeting ZEB1 and ZEB2
por: Hashiguchi, Yuma, et al.
Publicado: (2018)

Tamoxifen reverses epithelial–mesenchymal transition by demethylating miR-200c in triple-negative breast cancer cells
por: Wang, Qian, et al.
Publicado: (2017)

FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition
por: Dong, Tianxiu, et al.
Publicado: (2016)

Human Schlafen 5 regulates reversible epithelial and mesenchymal transitions in breast cancer by suppression of ZEB1 transcription
por: Wan, Guoqing, et al.
Publicado: (2020)

MiR-29b/TET1/ZEB2 signaling axis regulates metastatic properties and epithelial-mesenchymal transition in breast cancer cells
por: Wang, Hua, et al.
Publicado: (2017)

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
por: Kim, Taewan, et al.
Publicado: (2011)

The role of epithelial–mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel‐resistant prostate cancer
por: Hanrahan, Karen, et al.
Publicado: (2017)

53BP1 suppresses epithelial–mesenchymal transition by downregulating ZEB1 through microRNA-200b/429 in breast cancer
por: Kong, Xiangnan, et al.
Publicado: (2015)

miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells
por: NISHIJIMA, NOBUHIKO, et al.
Publicado: (2016)

Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion
por: Title, Alexandra C., et al.
Publicado: (2018)

UTMD inhibit EMT of breast cancer through the ROS/miR-200c/ZEB1 axis
por: Shi, Dandan, et al.
Publicado: (2020)

The miR-200–Zeb1 axis regulates key aspects of β-cell function and survival in vivo
por: Title, Alexandra C., et al.
Publicado: (2021)

The miR-200c/141-ZEB2-TGFb axis is aberrant in human T-cell prolymphocytic leukemia
por: Erkeland, Stefan J., et al.
Publicado: (2021)

Dynamics and plasticity of the epithelial to mesenchymal transition induced by miR-200 family inhibition
por: Haraguchi, Takeshi, et al.
Publicado: (2016)

Long noncoding RNA MAGI1-IT1 promoted invasion and metastasis of epithelial ovarian cancer via the miR-200a/ZEB axis
por: Gao, Hao, et al.
Publicado: (2019)

LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway
por: Li, Shi-Peng, et al.
Publicado: (2016)

Interleukin-8 Promotes Epithelial-to-Mesenchymal Transition via Downregulation of Mir-200 Family in Breast Cancer Cells
por: Zhang, Jin, et al.
Publicado: (2020)

The Tetraindole SK228 Reverses the Epithelial-to-Mesenchymal Transition of Breast Cancer Cells by Up-Regulating Members of the miR-200 Family
por: Wang, Chie-Hong, et al.
Publicado: (2014)

miR-1271 inhibits growth, invasion and epithelial–mesenchymal transition by targeting ZEB1 in ovarian cancer cells
por: Jiao, Yanni, et al.
Publicado: (2019)

MicroRNA-200c inhibits the metastasis of non-small cell lung cancer cells by targeting ZEB2, an epithelial-mesenchymal transition regulator
por: Jiao, Aihong, et al.
Publicado: (2021)

The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis
por: Wang, Jue, et al.
Publicado: (2017)

Long non-coding RNA ZFAS1 is a major regulator of epithelial-mesenchymal transition through miR-200/ZEB1/E-cadherin, vimentin signaling in colon adenocarcinoma
por: O’Brien, Stephen J., et al.
Publicado: (2021)

HOTAIR/miR-1277-5p/ZEB1 axis mediates hypoxia-induced oxaliplatin resistance via regulating epithelial-mesenchymal transition in colorectal cancer
por: Weng, Xingyue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nvg74fcojima77955745rvtvcg