Inactivation of ID4 promotes a CRPC phenotype with constitutive AR activation through FKBP52

Castration‐resistant prostate cancer (CRPC) is the emergence of prostate cancer cells that have adapted to the androgen‐depleted environment of the prostate. In recent years, targeting multiple chaperones and co‐chaperones (e.g., Hsp27, FKBP52) that promote androgen receptor (AR) signaling and/or no...

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Detalles Bibliográficos
Autores principales: Joshi, Jugal Bharat, Patel, Divya, Morton, Derrick J., Sharma, Pankaj, Zou, Jin, Hewa Bostanthirige, Dhanushka, Gorantla, Yamini, Nagappan, Peri, Komaragiri, Shravan Kumar, Sivils, Jeffrey C., Xie, Huan, Palaniappan, Ravi, Wang, Guangdi, Cox, Marc B., Chaudhary, Jaideep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378613/
https://www.ncbi.nlm.nih.gov/pubmed/28252832
http://dx.doi.org/10.1002/1878-0261.12028

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