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Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders
The unique biology of RNA binding proteins is altering our view of the genesis of protein misfolding diseases. These proteins use aggregation of low complexity domains (LCDs) as a means to regulate the localization and utilization of RNA by forming RNA granules, such as stress granules, transport gr...
Autores principales: | Maziuk, Brandon, Ballance, Heather I., Wolozin, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378767/ https://www.ncbi.nlm.nih.gov/pubmed/28420962 http://dx.doi.org/10.3389/fnmol.2017.00089 |
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