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Outlining Core Pathways of Amyloid Toxicity in Bacteria with the RepA-WH1 Prionoid
The synthetic bacterial prionoid RepA-WH1 causes a vertically transmissible amyloid proteinopathy in Escherichia coli that inhibits growth and eventually kills the cells. Recent in vitro studies show that RepA-WH1 builds pores through model lipid membranes, suggesting a possible mechanism for bacter...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378768/ https://www.ncbi.nlm.nih.gov/pubmed/28421043 http://dx.doi.org/10.3389/fmicb.2017.00539 |