An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin

This case suggests that initiation of HCV therapy immediately after liver transplantation with well‐tolerated, all‐oral regimens may achieve a virologic cure in HCV‐positive recipients, thus preventing post‐transplant HCV recurrence and associated disease progression. This strategy may broaden utili...

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Detalles Bibliográficos
Autores principales: Poordad, Fred, Lawitz, Eric, Gutierrez, Julio A., Guerrero, Juan, Speeg, Kermit, Swenson, Eugene S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378822/
https://www.ncbi.nlm.nih.gov/pubmed/28396749
http://dx.doi.org/10.1002/ccr3.841
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author Poordad, Fred
Lawitz, Eric
Gutierrez, Julio A.
Guerrero, Juan
Speeg, Kermit
Swenson, Eugene S.
author_facet Poordad, Fred
Lawitz, Eric
Gutierrez, Julio A.
Guerrero, Juan
Speeg, Kermit
Swenson, Eugene S.
author_sort Poordad, Fred
collection PubMed
description This case suggests that initiation of HCV therapy immediately after liver transplantation with well‐tolerated, all‐oral regimens may achieve a virologic cure in HCV‐positive recipients, thus preventing post‐transplant HCV recurrence and associated disease progression. This strategy may broaden utilization of HCV‐positive donor livers, potentially including HCV‐negative transplant recipients.
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spelling pubmed-53788222017-04-10 An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin Poordad, Fred Lawitz, Eric Gutierrez, Julio A. Guerrero, Juan Speeg, Kermit Swenson, Eugene S. Clin Case Rep Case Reports This case suggests that initiation of HCV therapy immediately after liver transplantation with well‐tolerated, all‐oral regimens may achieve a virologic cure in HCV‐positive recipients, thus preventing post‐transplant HCV recurrence and associated disease progression. This strategy may broaden utilization of HCV‐positive donor livers, potentially including HCV‐negative transplant recipients. John Wiley and Sons Inc. 2017-02-03 /pmc/articles/PMC5378822/ /pubmed/28396749 http://dx.doi.org/10.1002/ccr3.841 Text en © 2017 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Poordad, Fred
Lawitz, Eric
Gutierrez, Julio A.
Guerrero, Juan
Speeg, Kermit
Swenson, Eugene S.
An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
title An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
title_full An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
title_fullStr An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
title_full_unstemmed An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
title_short An HCV‐positive recipient of an HCV‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
title_sort hcv‐positive recipient of an hcv‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378822/
https://www.ncbi.nlm.nih.gov/pubmed/28396749
http://dx.doi.org/10.1002/ccr3.841
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