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Seroepidemiology of mumps in the general population of Jiangsu province, China after introduction of a one-dose measles-mumps-rubella vaccine

The mumps surveillance data from 2004 to 2011 showed that the incidence of mumps remained high after the one-dose measles-mumps-rubella (MMR) vaccine was introduced in China in 2008. A cross-sectional survey of mumps IgG in the general population of Jiangsu province was conducted in 2012 to gain com...

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Autores principales: Liu, Yuanbao, Hu, Ying, Deng, Xiuying, Wang, Zhiguo, Lu, Peishan, Ma, Fubao, Zhou, Minghao, Liu, Pei, Min, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378901/
https://www.ncbi.nlm.nih.gov/pubmed/26423223
http://dx.doi.org/10.1038/srep14660
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author Liu, Yuanbao
Hu, Ying
Deng, Xiuying
Wang, Zhiguo
Lu, Peishan
Ma, Fubao
Zhou, Minghao
Liu, Pei
Min, Jie
author_facet Liu, Yuanbao
Hu, Ying
Deng, Xiuying
Wang, Zhiguo
Lu, Peishan
Ma, Fubao
Zhou, Minghao
Liu, Pei
Min, Jie
author_sort Liu, Yuanbao
collection PubMed
description The mumps surveillance data from 2004 to 2011 showed that the incidence of mumps remained high after the one-dose measles-mumps-rubella (MMR) vaccine was introduced in China in 2008. A cross-sectional survey of mumps IgG in the general population of Jiangsu province was conducted in 2012 to gain comprehensive information on the immunity profile of the general population. The mean incidence was 15.2 per 100 000 individuals in Jiangsu province from 2004–2013. Two mumps incidence peaks were observed each year after introduction of the one-dose MMR vaccine. The seroprevalence did not significantly differ by region or sex, while the GMC significantly differed by region and sex. The overall GMC in Jiangsu province was 99.1 IU/ml (95% CI: 90.1–108.2), while the seroprevalence was only 59.1% (95% CI: 56.5–61.6). The seroprevalences for the 2 age groups that received the one-dose MMR vaccine, with reported coverage exceeding 95%, were 42.6% and 70.0%, respectively. The data on the incidence, MMR coverage, and seroprevalence in children younger than 6 years of age indicate that a two-dose MMR strategy should be considered. Mumps surveillance should be strengthened in children aged 6–11 and in those aged 12–17 because of their high contact rates and relatively low seroprevalences.
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spelling pubmed-53789012017-04-07 Seroepidemiology of mumps in the general population of Jiangsu province, China after introduction of a one-dose measles-mumps-rubella vaccine Liu, Yuanbao Hu, Ying Deng, Xiuying Wang, Zhiguo Lu, Peishan Ma, Fubao Zhou, Minghao Liu, Pei Min, Jie Sci Rep Article The mumps surveillance data from 2004 to 2011 showed that the incidence of mumps remained high after the one-dose measles-mumps-rubella (MMR) vaccine was introduced in China in 2008. A cross-sectional survey of mumps IgG in the general population of Jiangsu province was conducted in 2012 to gain comprehensive information on the immunity profile of the general population. The mean incidence was 15.2 per 100 000 individuals in Jiangsu province from 2004–2013. Two mumps incidence peaks were observed each year after introduction of the one-dose MMR vaccine. The seroprevalence did not significantly differ by region or sex, while the GMC significantly differed by region and sex. The overall GMC in Jiangsu province was 99.1 IU/ml (95% CI: 90.1–108.2), while the seroprevalence was only 59.1% (95% CI: 56.5–61.6). The seroprevalences for the 2 age groups that received the one-dose MMR vaccine, with reported coverage exceeding 95%, were 42.6% and 70.0%, respectively. The data on the incidence, MMR coverage, and seroprevalence in children younger than 6 years of age indicate that a two-dose MMR strategy should be considered. Mumps surveillance should be strengthened in children aged 6–11 and in those aged 12–17 because of their high contact rates and relatively low seroprevalences. Nature Publishing Group 2015-10-01 /pmc/articles/PMC5378901/ /pubmed/26423223 http://dx.doi.org/10.1038/srep14660 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Liu, Yuanbao
Hu, Ying
Deng, Xiuying
Wang, Zhiguo
Lu, Peishan
Ma, Fubao
Zhou, Minghao
Liu, Pei
Min, Jie
Seroepidemiology of mumps in the general population of Jiangsu province, China after introduction of a one-dose measles-mumps-rubella vaccine
title Seroepidemiology of mumps in the general population of Jiangsu province, China after introduction of a one-dose measles-mumps-rubella vaccine
title_full Seroepidemiology of mumps in the general population of Jiangsu province, China after introduction of a one-dose measles-mumps-rubella vaccine
title_fullStr Seroepidemiology of mumps in the general population of Jiangsu province, China after introduction of a one-dose measles-mumps-rubella vaccine
title_full_unstemmed Seroepidemiology of mumps in the general population of Jiangsu province, China after introduction of a one-dose measles-mumps-rubella vaccine
title_short Seroepidemiology of mumps in the general population of Jiangsu province, China after introduction of a one-dose measles-mumps-rubella vaccine
title_sort seroepidemiology of mumps in the general population of jiangsu province, china after introduction of a one-dose measles-mumps-rubella vaccine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378901/
https://www.ncbi.nlm.nih.gov/pubmed/26423223
http://dx.doi.org/10.1038/srep14660
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