Selective in vivo and in vitro activities of 3,3′-4-nitrobenzylidene-bis-4-hydroxycoumarin against methicillin-resistant Staphylococcus aureus by inhibition of DNA polymerase III

As the persistent resistance of Staphylococcus aureus to available antibiotics is associated with high infection incidence, mortality rate and treatment cost, novel antibacterial agents with innovative therapeutic targets must be developed. 3,3′-(4-Nitrobenzylidene)-bis-(4-hydroxycoumarin) (NBH), a...

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Detalles Bibliográficos
Autores principales: Hou, Zheng, Zhou, Ying, Li, Jing, Zhang, Xinlei, Shi, Xin, Xue, Xiaoyan, Li, Zhi, Ma, Bo, Wang, Yukun, Li, Mingkai, Luo, Xiaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378903/
https://www.ncbi.nlm.nih.gov/pubmed/26323712
http://dx.doi.org/10.1038/srep13637

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