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Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase

The current Zika virus (ZIKV) outbreak became a global health threat of complex epidemiology and devastating neurological impacts, therefore requiring urgent efforts towards the development of novel efficacious and safe antiviral drugs. Due to its central role in RNA viral replication, the non-struc...

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Detalles Bibliográficos
Autores principales: Godoy, Andre S., Lima, Gustavo M. A., Oliveira, Ketllyn I. Z., Torres, Naiara U., Maluf, Fernando V., Guido, Rafael V. C., Oliva, Glaucius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378953/
https://www.ncbi.nlm.nih.gov/pubmed/28345596
http://dx.doi.org/10.1038/ncomms14764